A very recent, 2016 research article compared the topical moisturizing effect of crosslinked HA (not Hylan B gel specifically, but something called Resilient HA or RHA), HMW-HA and LMW-HA and found that "TEWL (that is trans-epidermal water loss, the water that evaporates from the skin) was reduced by 27.8% with RHA, and by 15.6% with HMW HA, but increased by 55.5% with LMW HA." (You can read much more about HMW and LMW HA here in the geeky details section.) All in all, we think Sodium Hyaluronate Crosspolymer is an awesome version of HA , probably superior to traditional versions, so be happy to spot it on the ingredient list
That same study suggested that taking a GLP-1 for 1.5 years or more was associated with a 2.32 times higher chance of a deep vein thrombosis
Drucker DJ, Dritselis A, Kirkpatrick P
Zhonghua Nan.Ke.Xue 2012;18(5):428-431
A few hours outside the fridge, or even overnight at moderate room temperature, falls within the range these products are designed to handle
